Common Ground - Synthesis of Biology
Overcoming adversity, one optimized model at a time.
To successfully inform, educate and raise awareness about the field of systems biology, we understand the importance of great storytelling. Mathematics and biology generally have a connotation of being boring subjects, but when combined to deliver on exciting applications, it amplifies engagement and understanding. On one hand, biochemistry and biophysics delivers on accurate reconstructions of biological networks. This gives us information on events such as which molecules talk and listen to each other, which ones need the help of mediators for more constructive conversations, which groups like to work together when constructing and deconstructing, and what time and with what frequency parties are talking, listening, forming coalitions, and breaking up with each other. On the other hand, mathematics helps us tap into the power of prediction and prescription. Models allow us to ask and answer questions such as which groups are likely to listen to each other? what time and place will constructions and deconstructions take place? who needs to be present? what is likely to happen if we disrupt or facilitate certain interactions? what are the most efficient ways to intervene? etc.
It is amazing that simple building blocks of series of events lead to complex and intelligent systems. This brings us to the question, what is possible as we master these networks? What questions can we ask and what questions can we answer? What insights can cellular intelligence give us when designing artificial general intelligence? How precise can precision medicine be? What will our evolution likely look like as our environment evolves? How do we design more efficient bioeconomies?